NalO(4)/LiBr-mediated diastereoselective dihydroxylation of olefins: a catalytic approach to the prevost-woodward reaction

TitleNalO(4)/LiBr-mediated diastereoselective dihydroxylation of olefins: a catalytic approach to the prevost-woodward reaction
Publication TypeJournal Article
Year of Publication2005
AuthorsEmmanuvel, L, Shaikh, TMA, Sudalai, A
JournalOrganic Letters
Volume7
Issue22
Pagination5071-5074
Date PublishedOCT
Type of ArticleArticle
ISSN1523-7060
Abstract

LlBr catalyzes efficiently the dihydroxylation of alkenes to afford syn and anti diols with excellent diastereoselectivity depending upon the use of NaIO4 (30 mol %) or Phl(OAc)(2) (1 equiv), respectively, as the oxidants. The oxidation of non-benzylic halides has been achieved for the first time to afford the corresponding diols in excellent yields.

DOI10.1021/ol052080n
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)6.732
Divison category: 
Chemical Engineering & Process Development