N-Heterocyclic carbene catalyzed oxidative coupling of alkenes/alpha-bromoacetophenones with aldehydes: a facile entry to alpha,beta-epoxy ketones
| Title | N-Heterocyclic carbene catalyzed oxidative coupling of alkenes/alpha-bromoacetophenones with aldehydes: a facile entry to alpha,beta-epoxy ketones |
| Publication Type | Journal Article |
| Year of Publication | 2015 |
| Authors | Reddi, RN, Prasad, PK, Sudalai, A |
| Journal | Angewandte Chemie-International Edition |
| Volume | 54 |
| Issue | 47 |
| Pagination | 14150-14153 |
| Date Published | NOV |
| ISSN | 1433-7851 |
| Keywords | aldehydes, epoxidation, N-heterocyclic carbenes, Oxidation, synthetic methods |
| Abstract | {A novel, N-heterocyclic carbene (NHC) catalyzed direct oxidative coupling of styrenes with aldehydes has been described for the synthesis of alpha,beta-epoxy ketones in good yields. This unprecedented regioselective oxidative coupling employs NBS/DBU/DMSO (DBU = 1,8-diazabicyclo [5.4. 0] undec-7-ene |
| DOI | 10.1002/anie.201507363 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 11.709 |
Divison category:
Chemical Engineering & Process Development