N-heterocyclic carbene-catalyzed cascade reaction involving the hydroacylation of unactivated alkynes
| Title | N-heterocyclic carbene-catalyzed cascade reaction involving the hydroacylation of unactivated alkynes |
| Publication Type | Journal Article |
| Year of Publication | 2010 |
| Authors | Biju, AT, Wurz, NE, Glorius, F |
| Journal | Journal of the American Chemical Society |
| Volume | 132 |
| Issue | 17 |
| Pagination | 5970–5971 |
| Date Published | APR |
| Abstract | The N-heterocyclic carbene (NHC)-catalyzed hydroacylation of unactivated alkynes to provide α,β-unsaturated ketones is reported. In addition, a rare case of an efficient and selective dually NHC-catalyzed cascade reaction involving the hydroacylation of alkynes and a subsequent intermolecular Stetter reaction allows the formation of chromanones containing a 1,4-diketone moiety. |
| DOI | 10.1021/ja102130s |
| Funding Agency | Council of Scientific & Industrial Research (CSIR) - India |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 9.019 |
Divison category:
Organic Chemistry