Multi-component carbon-carbon bond forming Mannich reaction catalyzed by yttria-zirconia based Lewis acid

TitleMulti-component carbon-carbon bond forming Mannich reaction catalyzed by yttria-zirconia based Lewis acid
Publication TypeJournal Article
Year of Publication2008
AuthorsRamalingam, S, Kumar, P
JournalCatalysis Communications
Volume9
Issue14
Pagination2445-2448
Date PublishedAUG
ISSN1566-7367
Keywordsbeta-amino carbonyls, Mannich reaction, multi-component reaction, yttria-zirconia based Lewis acid
Abstract

A direct three component Mannich-type reaction of aldehyde, amine, and ketone (without silyl enolates) were efficiently catalyzed by yttria-zirconia based strong Lewis acid in aqueous acetonitrile. (C) 2008 Elsevier B.V. All rights reserved.

DOI10.1016/j.catcom.2008.06.011
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.827
Divison category: 
Organic Chemistry