Metal-free regioselective cross dehydrogenative coupling of cyclic ethers and aryl carbonyls
Title | Metal-free regioselective cross dehydrogenative coupling of cyclic ethers and aryl carbonyls |
Publication Type | Journal Article |
Year of Publication | 2019 |
Authors | Mane, KD, Mukherjee, A, Vanka, K, Suryavanshi, G |
Journal | Journal of Organic Chemistry |
Volume | 84 |
Issue | 4 |
Pagination | 2039-2047 |
Date Published | FEB |
Type of Article | Article |
ISSN | 0022-3263 |
Abstract | A highly regioselective, efficient, and metal-free oxidative cross dehydrogenative coupling (CDC) of aryl carbonyls with cyclic ethers has been developed. This method offers easy access to substituted alpha-arylated cyclic ethers with a high functional group tolerance in good to excellent yields. The regioselectivity of this CDC reaction was confirmed by density functional theory (DFT)-based calculations. |
DOI | 10.1021/acs.joc.8b03048 |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 4.745 |
Divison category:
Chemical Engineering & Process Development
Physical and Materials Chemistry
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