Metal-free regioselective cross dehydrogenative coupling of cyclic ethers and aryl carbonyls

TitleMetal-free regioselective cross dehydrogenative coupling of cyclic ethers and aryl carbonyls
Publication TypeJournal Article
Year of Publication2019
AuthorsMane, KD, Mukherjee, A, Vanka, K, Suryavanshi, G
JournalJournal of Organic Chemistry
Volume84
Issue4
Pagination2039-2047
Date PublishedFEB
Type of ArticleArticle
ISSN0022-3263
Abstract

A highly regioselective, efficient, and metal-free oxidative cross dehydrogenative coupling (CDC) of aryl carbonyls with cyclic ethers has been developed. This method offers easy access to substituted alpha-arylated cyclic ethers with a high functional group tolerance in good to excellent yields. The regioselectivity of this CDC reaction was confirmed by density functional theory (DFT)-based calculations.

DOI10.1021/acs.joc.8b03048
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

4.745

Divison category: 
Chemical Engineering & Process Development
Physical and Materials Chemistry

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