Metal-free isoamyl nitrite mediated efficient synthesis of 1,2,4-oxadiazoles
| Title | Metal-free isoamyl nitrite mediated efficient synthesis of 1,2,4-oxadiazoles |
| Publication Type | Journal Article |
| Year of Publication | 2023 |
| Authors | Galave, SA, Kadam, KS, Sonawane, AD, Pansare, VR, Garud, DR |
| Journal | Tetrahedron Letters |
| Volume | 125 |
| Pagination | 154616 |
| Date Published | JUL |
| Type of Article | Article |
| ISSN | 0040-4039 |
| Keywords | 1, 2, 4-Oxadiazole, Aldoxime, Cycloaddition, Isoamyl nitrite |
| Abstract | We report herein, a metal-free isoamyl nitrite mediated efficient synthesis of 1,2,4-oxadiazoles by one pot cycloaddition reaction of aldoximes with nitriles. The structure of the 1,2,4-oxadiazole derivatives was confirmed by studies of spectral analysis. Current methodology provides a novel pathway to access 1,2,4-oxadiazole derivatives.& COPY; 2023 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetlet.2023.154616 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 1.8 |
Divison category:
Organic Chemistry
Database:
Web of Science (WoS)