Metal-free, acid-catalyzed 1,6-conjugate addition of NH-sulfoximines to para-quinone methides: accessing to diarylmethine imino sulfanone
| Title | Metal-free, acid-catalyzed 1,6-conjugate addition of NH-sulfoximines to para-quinone methides: accessing to diarylmethine imino sulfanone |
| Publication Type | Journal Article |
| Year of Publication | 2021 |
| Authors | More, SG, Rupanawar, BD, Suryavanshi, G |
| Journal | Journal of Organic Chemistry |
| Volume | 86 |
| Issue | 15 |
| Pagination | 10129-10139 |
| Date Published | AUG |
| Type of Article | Article |
| ISSN | 0022-3263 |
| Abstract | We have reported an efficient and metal-free method for the construction of alpha-diarylmethine imino sulfanone using acid-catalyzed 1,6-conjugate addition of sulfoximines on para-quinine methides (p-QMs). This method showed broad functional group tolerance and a wide range of substrate scope with good to excellent yield. The excellent protocol exhibits mild reaction conditions with high atom economy. The practicability of the present method was supported by a Gram-scale reaction. |
| DOI | 10.1021/acs.joc.1c00869 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 4.354 |
Divison category:
Chemical Engineering & Process Development
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