Metal- and light-free direct C-3 ketoalkylation of quinoxalin-2(1H)-ones with cyclopropanols in aqueous medium
| Title | Metal- and light-free direct C-3 ketoalkylation of quinoxalin-2(1H)-ones with cyclopropanols in aqueous medium |
| Publication Type | Journal Article |
| Year of Publication | 2022 |
| Authors | More, DA, Mujahid, M, Muthukrishnan, M |
| Journal | ChemistrySelect |
| Volume | 7 |
| Issue | 39 |
| Pagination | e202203597 |
| Date Published | OCT |
| Type of Article | Article |
| ISSN | 2365-6549 |
| Keywords | aqueous medium, cyclopropanols, ketoalkylation, metal-free, quinoxalin-2(1H)-ones |
| Abstract | Direct oxidative C-3 ketoalkylation of quinoxalin-2(1H)-ones with cyclopropanols using ammonium persulfate in an aqueous medium has been achieved in a moderate to good yield. The reaction does not require metals, light-source, or catalysts to facilitate the reaction and could be efficiently utilized to construct a wide range of biologically relevant 3-ketoalkylated quinoxalin-2(1H)-ones. |
| DOI | 10.1002/slct.202203597 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.307 |
Divison category:
Organic Chemistry
Database:
Web of Science (WoS)