Manganese-catalyzed direct C-C coupling of -C-H bonds of amides and esters with alcohols via hydrogen autotransfer

TitleManganese-catalyzed direct C-C coupling of -C-H bonds of amides and esters with alcohols via hydrogen autotransfer
Publication TypeJournal Article
Year of Publication2019
AuthorsRana, J, Gupta, V, Balaraman, E
JournalDalton Transactions
Volume48
Issue21
Pagination7094-7099
Date PublishedJUN
Type of ArticleArticle
ISSN1477-9226
Abstract

Herein we report an efficient manganese-catalyzed C-alkylation of unactivated amides and tert-butyl acetate using alcohols as alkylating agents. This elegant approach exhibits a broad substrate scope providing the C-C coupled products of amides via a hydrogen auto-transfer strategy using aryl, heteroaryl, and aliphatic alcohols.

DOI10.1039/c8dt05020a
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

4.052

Divison category: 
Organic Chemistry

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