Isa-NHC-catalyzed intermolecular stetter reaction of aromatic aldehydes with maleimides: an efficient access to 3-aroylsuccinimides
| Title | Isa-NHC-catalyzed intermolecular stetter reaction of aromatic aldehydes with maleimides: an efficient access to 3-aroylsuccinimides |
| Publication Type | Journal Article |
| Year of Publication | 2018 |
| Authors | Ahire, MM, Mhaske, SB |
| Journal | Tetrahedron |
| Volume | 76 |
| Issue | 16 |
| Pagination | 2079-2084 |
| Date Published | APR |
| Abstract | An intermolecular Stetter reaction of aromatic aldehydes with maleimides has been developed using thiazolylidene salt derived Isa-NHC as an efficient organocatalyst. The synthesized Stetter products "3-aroylsuccinimides" are important building blocks for the synthesis of natural products and bioactive compounds. The reaction conditions are mild, and various substituents on aromatic aldehyde and maleimide nitrogen were tolerated. (C) 2018 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tet.2018.03.009 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.651 |
Divison category:
Organic Chemistry
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