Ir(III)-catalyzed carbenoid functionalization of benzamides: synthesis of N-methoxyisoquinolinediones and N-methoxyisoquinolinones

TitleIr(III)-catalyzed carbenoid functionalization of benzamides: synthesis of N-methoxyisoquinolinediones and N-methoxyisoquinolinones
Publication TypeJournal Article
Year of Publication2016
AuthorsPhatake, RS, Patel, P, Ramana, CV
JournalOrganic Letters
Volume18
Issue12
Pagination2828-2831
Date PublishedJUN
ISSN1523-7060
Abstract

A mild and efficient Ir(III)-catalyzed C-H carbenoid functionalization strategy has been developed to access. N-methoxyisoquinolinediones and N-methoxyisoquinolinones. The reaction proceeds efficiently in high yield at room temperature over a broad range of substrates without requirement of any additional oxidants or a base.

DOI10.1021/acs.orglett.6b01072
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)6.732
Divison category: 
Organic Chemistry