Iodine-catalyzed aromatization of tetrahydrocarbazoles and its utility in the synthesis of glycozoline and murrayafoline A: a combined experimental and computational investigation
| Title | Iodine-catalyzed aromatization of tetrahydrocarbazoles and its utility in the synthesis of glycozoline and murrayafoline A: a combined experimental and computational investigation |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Humne, VT, Dangat, YB, Vanka, K, Lokhande, P |
| Journal | Organic & Biomolecular Chemistry |
| Volume | 12 |
| Issue | 27 |
| Pagination | 4832-4836 |
| Date Published | JUN |
| ISSN | 1477-0520 |
| Abstract | A new protocol for the aromatization of tetrahydrocarbazoles has been achieved using a catalytic amount of iodine, giving high yields. The role of iodine in the aromatization has been explained by DFT, and its wide scope is extended to the total synthesis of glycozoline and murrayafoline A. This method has proven to be tolerant of a broad range of functional groups. |
| DOI | 10.1039/c4ob00635f |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.93 |
Divison category:
Physical and Materials Chemistry