Insights from a pan India Sero-epidemiological survey (Phenome-India Cohort) for SARS-CoV2
| Title | Insights from a pan India Sero-epidemiological survey (Phenome-India Cohort) for SARS-CoV2 |
| Publication Type | Journal Article |
| Year of Publication | 2021 |
| Authors | Naushin, S, Sardana, V, Ujjainiya, R, Bhatheja, N, Kutum, R, Bhaskar, AKumar, Pradhan, S, Prakash, S, Khan, R, Rawat, BSingh, Tallapaka, KBharadwaj, Anumalla, M, Chandak, GRatan, Lahiri, A, Kar, S, Mulay, SRamesh, Mugale, MNilakanth, Srivastava, M, Khan, S, Srivastava, A, Tomar, B, Veerapandian, M, Venkatachalam, G, Vijayakumar, SRaja, Agarwal, A, Gupta, D, Halami, PM, Peddha, MServa, Sundaram, GM, Veeranna, RP, Pal, A, Agarwal, VKumar, Maurya, AKu, Singh, RKumar, Raman, AKumar, Anandasadagopan, SKumar, Karuppanan, P, Venkatesan, S, Sardana, HKumar, Kothari, A, Jain, R, Thakur, A, Parihar, DSingh, Saifi, A, Kaur, J, Kumar, V, Mishra, A, Gogeri, I, Rayasam, G, Singh, P, Chakraborty, R, Chaturvedi, G, Karunakar, P, Yadav, R, Singhmar, S, Singh, D, Sarkar, S, Bhattacharya, P, Acharya, S, Singh, V, Verma, S, Soni, D, Seth, S, Vashisht, S, Thakran, S, Fatima, F, Singh, APratap, Sharma, A, Sharma, B, Subramanian, M, Padwad, YS, Hallan, V, Patial, V, Singh, D, Tripude, NVijay, Chakrabarti, P, Maity, SKrishna, Ganguly, D, Sarkar, J, Ramakrishna, S, Kumar, BNarender, Kumar, KA, Gandhi, SG, Jamwal, PSingh, Chouhan, R, Jamwal, VLakshmi, Kapoor, N, Ghosh, D, Thakkar, G, Subudhi, U, Sen, P, Chaudhury, SRay, Kumar, R, Gupta, P, Tuli, A, Sharma, D, Ringe, RP, Amarnarayan, D, Kulkarni, M, Shanmugam, D, Dharne, MS, Dastager, SG, Joshi, R, Patil, AP, Mahajan, SN, Khan, AHabib, Wagh, V, Yadav, RKumar, Khilari, A, Bhadange, M, Chaurasiya, AH, Kulsange, SE, Khairnar, K, Paranjape, S, Kalita, J, Sastry, NG, Phukan, T, Manna, P, Romi, W, Bharali, P, Ozah, D, Sahu, RKumar, Babu, EVssk, Sukumaran, R, Nair, AR, Valappil, PKooloth, Puthiyamadam, A, Velayudhanpillai, A, Chodankar, K, Damare, S, Madhavi, Y, Aggarwal, VVarun, Dahiya, S, Agrawal, A, Dash, D, Sengupta, S |
| Journal | eLife |
| Volume | 10 |
| Pagination | e66537 |
| Date Published | APR |
| Type of Article | Article |
| ISSN | 2050-084X |
| Abstract | To understand the spread of SARS-CoV2, in August and September 2020, the Council of Scientific and Industrial Research (India) conducted a serosurvey across its constituent laboratories and centers across India. Of 10,427 volunteers, 1058 (10.14%) tested positive for SARS-CoV2 anti-nucleocapsid (anti-NC) antibodies, 95% of which had surrogate neutralization activity. Three-fourth of these recalled no symptoms. Repeat serology tests at 3 (n = 607) and 6 (n = 175) months showed stable anti-NC antibodies but declining neutralization activity. Local seropositivity was higher in densely populated cities and was inversely correlated with a 30-day change in regional test positivity rates (TPRs). Regional seropositivity above 10% was associated with declining TPR. Personal factors associated with higher odds of seropositivity were high-exposure work (odds ratio, 95% confidence interval, p value: 2.23, 1.92-2.59, <0.0001), use of public transport (1.79, 1.43-2.24, <0.0001), not smoking (1.52, 1.16-1.99, 0.0257), non-vegetarian diet (1.67, 1.41-1.99, <0.0001), and B blood group (1.36, 1.15-1.61, 0.001). |
| DOI | 10.7554/eLife.66537 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 8.140 |
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