Identification of N-glycosylation sites with sequence and structural features employing random forests

TitleIdentification of N-glycosylation sites with sequence and structural features employing random forests
Publication TypeJournal Article
Year of Publication2009
AuthorsKarnik, S, Mitra, J, Singh, A, Kulkarni, BD, Sundarajan, V, Jayaraman, VK
Secondary AuthorsChaudhury, S, Mitra, S, Murthy, CA, Sastry, PS, Pal, SK
JournalPattern Recognition and Machine Intelligence, Proceedings
Volume5909
Pagination146-151
Date PublishedDEC
ISBN Number978-3-642-11163-1
ISSN0302-9743
Abstract

N-Glycosylation plays a very important role in various processes like quality control of proteins produced in ER, transport of proteins and in disease control. The experimental elucidation of N-Glycosylation sites is expensive and laborious process. In this work we build models for identification of potential N-Glycosylation sites in proteins based on sequence and structural features. The best model has cross validation accuracy rate of 72.81%.

Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.607
Divison category: 
Chemical Engineering & Process Development