I-2-mediated regioselective C-3 azidation of indoles
| Title | I-2-mediated regioselective C-3 azidation of indoles |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Prasad, PK, Kalshetti, RG, Reddi, RN, Kamble, SP, Sudalai, A |
| Journal | Organic & Biomolecular Chemistry |
| Volume | 14 |
| Issue | 11 |
| Pagination | 3027-3030 |
| Date Published | FEB |
| ISSN | 1477-0520 |
| Abstract | An unprecedented synthesis of novel 3-azido indoles has been developed using I-2 and NaN3 in high yields and excellent regio-selectivity. The reaction proceeds under metal-free conditions at room temperature. Essentially, an umpolung in reactivity at the C-3 position of indole has been achieved by the activation of indoles with I-2. |
| DOI | 10.1039/c6ob00295a |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.559 |
Divison category:
Chemical Engineering & Process Development