Generic framework for crystallization processes using the population balance model and its applicability

TitleGeneric framework for crystallization processes using the population balance model and its applicability
Publication TypeJournal Article
Year of Publication2015
AuthorsShaikh, LJ, Bari, AH, Ranade, VV, Pandit, AB
JournalIndustrial & Engineering Chemistry Research
Volume54
Issue42
Pagination10539-10548
Date PublishedOCT
ISSN0888-5885
Abstract

A generic modeling framework for batch cooling crystallization processes has been developed to understand the crystallization process from operational and modeling point of view. The generic framework for crystallization process modeling incorporates the characteristic dimensions of crystals and polymorphic transformation, as well as the hydrodynamic mixing effects in the crystallizer. This Polyhedral Polymorphic Multizonal Population Balance (PPMPBM) model considers bottom-up and top-down approaches for specific systems with specific targets. The PPMPBM framework allows switching between complex and simple models to study different crystallization systems with different scenarios and combination thereof. This framework uses gPROMS software (PSE, UK) and the Microsoft Excel front-end, along with the Polytope module in Matlab, to predict the crystal size and shape evolution as well as supersaturation profiles inside the crystallizer, which can be implemented for various crystallization systems.

DOI10.1021/acs.iecr.5b01421
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)2.567
Divison category: 
Chemical Engineering & Process Development