General approach to 2,4-dialkyl-3-carboxybutyrolactones: an efficient synthesis of (+/-)-striatisporolide A and (+/-)-lichesterinic acid
Title | General approach to 2,4-dialkyl-3-carboxybutyrolactones: an efficient synthesis of (+/-)-striatisporolide A and (+/-)-lichesterinic acid |
Publication Type | Journal Article |
Year of Publication | 2010 |
Authors | Patel, RM, Argade, NP |
Journal | Indian Journal of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry |
Volume | 49 |
Issue | 8 |
Pagination | 1071-1075 |
Date Published | AUG |
ISSN | 0376-4699 |
Keywords | 2-Alkylidene-3-methylsuccinimides, dehydrative cyclizations, lichesterinic acid, OsO(4)-dihydroxylation, striatisporolide A, synthesis |
Abstract | Starting from 2-alkylidene-3-methylsuccinimides, simple and efficient synthesis of the natural products striatisporolide A. lichesterinic acid and lichesterylic acid have been demonstrated via an acid catalyzed hydrolysis, esterification, OsO(4)-dihydroxylation and dehydrative cyclization pathway. |
Type of Journal (Indian or Foreign) | Indian |
Impact Factor (IF) | 0.562 |
Divison category:
Organic Chemistry