FRET-based probe for monitoring pH changes in lipid-dense region of Hct116 cells

TitleFRET-based probe for monitoring pH changes in lipid-dense region of Hct116 cells
Publication TypeJournal Article
Year of Publication2015
AuthorsReddy, UG, Anila, HA, Ali, F, Taye, N, Chattopadhyay, S, Das, A
JournalOrganic Letters
Volume17
Issue22
Pagination5532-5535
Date PublishedNOV
ISSN1523-7060
Abstract

A rhodamine conjugate (L) with a pseudo Stokes shift of 165 nm is used for probing changes in solution pH under physiological conditions. This reagent is found to be nontoxic, and the luminescence response could be used for imaging changes in endogenous pH induced by dexamethanose (DMT) in the endoplasmic reticulum.

DOI10.1021/acs.orglett.5b02568
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)6.732
Divison category: 
Organic Chemistry