Formation of tertiary amides and H2 by dehydrogenative coupling of primary alcohols with secondary amines catalyzed by ruthenium bipyridine-based pincer complexes
| Title | Formation of tertiary amides and H2 by dehydrogenative coupling of primary alcohols with secondary amines catalyzed by ruthenium bipyridine-based pincer complexes |
| Publication Type | Journal Article |
| Year of Publication | 2013 |
| Authors | Srimani, D, Balaraman, E, Hu, P, Ben-David, Y, Milstein, D |
| Journal | Advanced Synthesis & Catalysis |
| Volume | 355 |
| Issue | 13 |
| Pagination | 2525–2530 |
| Date Published | SEP |
| Abstract | Dehydrogenative coupling of primary alcohols with secondary amines to form tertiary amides and dihydrogen (H2) is efficiently catalyzed by bipyridyl-based ruthenium pincer complexes (0.2–1 mol%) under neutral conditions (in case of the dearomatized complexes), or with added catalytic amount of base. The reaction is sensitive to steric hindrance; in the case of amidation of bulky secondary amines a less sterically hindered complex is more efficient. Selective acylation of primary amines in the presence of secondary amines was also demonstrated. |
| DOI | 10.1002/adsc.201300620 |
| Funding Agency | Council of Scientific & Industrial Research (CSIR) - India |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 5.542 |
Divison category:
Catalysis and Inorganic Chemistry