Fluorogenic BODIPY molecular rotor as an apoptosis marker
Title | Fluorogenic BODIPY molecular rotor as an apoptosis marker |
Publication Type | Journal Article |
Year of Publication | 2019 |
Authors | Ashokkumar, P, Ashoka, AHoskere, Collot, M, Das, A, Klymchenko, AS |
Journal | Chemical Communications |
Volume | 55 |
Issue | 48 |
Pagination | 6902-6905 |
Date Published | JUN |
Type of Article | Article |
ISSN | 1359-7345 |
Abstract | Based on a BODIPY molecular rotor and a zinc-dipicolylamine receptor, we designed a fluorogenic probe for the detection of apoptosis. Being poorly emissive in solution and with healthy cells, it selectively binds phosphatidylserine of early apoptotic cells and internalizes into late apoptotic cells, lighting up its green fluorescence. |
DOI | 10.1039/c9cc03242h |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 6.164 |
Divison category:
Organic Chemistry
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