Fluorescent probe for bisulfite ions: its application to two-photon tissue imaging

TitleFluorescent probe for bisulfite ions: its application to two-photon tissue imaging
Publication TypeJournal Article
Year of Publication2016
AuthorsAgarwalla, H, Pal, S, Paul, A, Jun, YWoong, Bae, J, Ahn, KHan, Srivastava, DN, Das, A
JournalJournal of Materials Chemistry B
Volume4
Issue48
Pagination7888-7894
Date PublishedDEC
AbstractA benzoxazinone based fluorescent probe for the specific and efficient detection of bisulfite ions in aqueous medium is described. The probe formed a bisulfite/sulphite adduct with an associated turn-on fluorescence response in the red wavelength region. No interference was observed in the detection process from all possible competing anions and molecules, including cyanide ion, cysteine, homocysteine and glutathione. In addition, the probe showed a fast response time, low detection limit, and cell membrane permeability. Furthermore, the probe was two-photon excitable, enabling imaging of endogenous bisulfite ions in HeLa cells as well as in deep tissues from different organs of mouse.
DOI10.1039/c6tb02637k
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)4.872
Divison category: 
Organic Chemistry