First asymmetric total synthesis of aspinolide A

TitleFirst asymmetric total synthesis of aspinolide A
Publication TypeJournal Article
Year of Publication2009
AuthorsChowdhury, PSarathi, Gupta, P, Kumar, P
JournalTetrahedron Letters
Volume50
Issue50
Pagination7018-7020
Date PublishedDEC
ISSN0040-4039
KeywordsDecanolides, epoxides, Hydrolytic kinetic resolution, Ring-closing metathesis
Abstract

The first total synthesis of aspinolide A has been achieved using ring-closing metathesis as a key step. The stereogenic centers were generated by means of hydrolytic kinetic resolution (HKR) of racemic epoxides. (C) 2009 Elsevier Ltd. All rights reserved.

DOI10.1016/j.tetlet.2009.09.151
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.618
Divison category: 
Organic Chemistry