Facile synthesis of rubrolide E

TitleFacile synthesis of rubrolide E
Publication TypeJournal Article
Year of Publication2005
AuthorsKar, A, Argade, NP
JournalSynthesis-Stuttgart
Issue14
Pagination2284-2286
Date PublishedSEP
Type of ArticleArticle
ISSN0039-7881
KeywordsKnoevenagel condensation, Meerwein coupling, N-phenylmaleimide, regioselective reduction, rubrolide E, Total synthesis
Abstract

A simple and efficient synthesis of rubrolide E (1e) has been demonstrated via Meerwein coupling reaction of para-anisyl-diazonium chloride with N-phenylmaleimide (2), regioselective reduction of para-anisylmaleic anhydride (4), Knoevenagel condensation of butyrolactone 5 with para-anisaldehyde and demethylation pathway.

DOI10.1055/s-2005-869995
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.652
Divison category: 
Organic Chemistry