Facile synthesis of the isoquinoline alkaloids doryanine and oxyhydrastinine

TitleFacile synthesis of the isoquinoline alkaloids doryanine and oxyhydrastinine
Publication TypeJournal Article
Year of Publication2014
AuthorsJangir, R, Gadre, SR, Argade, NP
JournalSynthesis-Stuttgart
Volume46
Issue14
Pagination1954-1956
Date PublishedJUL
ISSN0039-7881
Keywordsdehydration, homophthalic acid, homophthalimide, isoquinoline alkaloids, regioselective reduction
Abstract

Starting from 4,5-(methylenedioxy)homophthalic acid, a concise and efficient synthesis of the isoquinoline alkaloids dory-anine and oxyhydrastinine is described via the corresponding homophthalimide utilizing a one-pot regioselective reductive dehydration and catalytic hydrogenation pathway.

DOI10.1055/s-0033-1341158
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)2.06
Divison category: 
Organic Chemistry