Facile synthesis of gamma-ketophosphonates by an intermolecular stetter reaction onto vinylphosphonates

TitleFacile synthesis of gamma-ketophosphonates by an intermolecular stetter reaction onto vinylphosphonates
Publication TypeJournal Article
Year of Publication2014
AuthorsPatra, A, Bhunia, A, Biju, AT
JournalOrganic Letters
Volume16
Issue12
Pagination4798-4801
Date PublishedSEP
ISSN1523-7060
Abstract

The atom-economic and practical N-heterocyclic carbene (NHC) catalyzed Stetter reaction for the synthesis of gamma-ketophosphonates by the reaction of aromatic aldehydes with vinylphosphonates is reported. The NHC derived from N-mesitylimidazolium salt (IMes) was an effective catalyst for this transformation, and the products were formed in moderate to good yields.

DOI10.1021/ol502262d
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.17
Divison category: 
Organic Chemistry