Facile one-pot multi-component synthesis of spirooxindoles and 3, 3 `-disubstituted oxindoles via sp(3) C-H activation/functionalization of azaarenes

TitleFacile one-pot multi-component synthesis of spirooxindoles and 3, 3 `-disubstituted oxindoles via sp(3) C-H activation/functionalization of azaarenes
Publication TypeJournal Article
Year of Publication2017
AuthorsPathan, MY, Chavan, SS, Shaikh, TMY, Thorat, SH, Gonnade, RG, Mulla, SAR
JournalChemistryselect
Volume2
Issue28
Pagination9147-9152
Date PublishedSEP
Type of ArticleArticle
ISSN2365-6549
Keywords3, 3'-disubstituted oxindoles, azaarenes, silica-supported dodecatungstophosphoric acid (DTP/SiO2) catalyst, sp(3) C-H activation/functionalization, spirooxindoles
Abstract

A novel one-pot multicomponent reaction (MCR) protocol has been demonstrated for the first time for sustainable and facile synthesis of spirooxindoles and 3, 3 `-disubstituted oxindoles in an excellent yield via sp(3) C-H activation/functionalization of 2-methyl azaarenes and (2-azaaryl)methanes with isatin, active methylene compounds using eco-friendly heterogeneous, reusable silica-supported dodecatungstophosphoric acid (DTP/SiO2) catalyst.

DOI10.1002/slct.201701507
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

1.505

Divison category: 
Chemical Engineering & Process Development
Physical and Materials Chemistry

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