Facile one-pot multi-component synthesis of spirooxindoles and 3, 3 `-disubstituted oxindoles via sp(3) C-H activation/functionalization of azaarenes
| Title | Facile one-pot multi-component synthesis of spirooxindoles and 3, 3 `-disubstituted oxindoles via sp(3) C-H activation/functionalization of azaarenes |
| Publication Type | Journal Article |
| Year of Publication | 2017 |
| Authors | Pathan, MY, Chavan, SS, Shaikh, TMY, Thorat, SH, Gonnade, RG, Mulla, SAR |
| Journal | Chemistryselect |
| Volume | 2 |
| Issue | 28 |
| Pagination | 9147-9152 |
| Date Published | SEP |
| Type of Article | Article |
| ISSN | 2365-6549 |
| Keywords | 3, 3'-disubstituted oxindoles, azaarenes, silica-supported dodecatungstophosphoric acid (DTP/SiO2) catalyst, sp(3) C-H activation/functionalization, spirooxindoles |
| Abstract | A novel one-pot multicomponent reaction (MCR) protocol has been demonstrated for the first time for sustainable and facile synthesis of spirooxindoles and 3, 3 `-disubstituted oxindoles in an excellent yield via sp(3) C-H activation/functionalization of 2-methyl azaarenes and (2-azaaryl)methanes with isatin, active methylene compounds using eco-friendly heterogeneous, reusable silica-supported dodecatungstophosphoric acid (DTP/SiO2) catalyst. |
| DOI | 10.1002/slct.201701507 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 1.505 |
Divison category:
Chemical Engineering & Process Development
Physical and Materials Chemistry
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