Excellent exo/endo-selectivity in the 1,3-dipolar cycloaddition of cyclic azomethine ylide: exploring the facile investigation of cocaine antagonists

TitleExcellent exo/endo-selectivity in the 1,3-dipolar cycloaddition of cyclic azomethine ylide: exploring the facile investigation of cocaine antagonists
Publication TypeJournal Article
Year of Publication2007
AuthorsLaha, JK
JournalLetters in Organic Chemistry
Volume4
Start PageJAN
Issue8
Pagination550-552
Date PublishedJAN
Type of ArticleArticle
ISSN1570-1786
Keywords1, 3-dipolar cycloaddition, cocaine antagonists, cyclic azomethine ylide, exo/endo-selectivity., tropane
Abstract

High exo-selectivity was achieved in the 1,3-dipolar cycloaddition of a cyclic azomethine ylide and phenyl vinyl sulfone or Opplozer's camphorsultam chiral dipolarophile leading to the synthesis of two novel tropane compounds.

DOI10.2174/157017807782795448
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

0.756

Divison category: 
Organic Chemistry