Enantioselective total synthesis of (2S,3R,4R)-D-xylo-phytosphingosine from substituted azetidin-2-one

TitleEnantioselective total synthesis of (2S,3R,4R)-D-xylo-phytosphingosine from substituted azetidin-2-one
Publication TypeJournal Article
Year of Publication2009
AuthorsPandey, G, Tiwari, DKumar
JournalTetrahedron Letters
Volume50
Issue26
Pagination3296-3298
Date PublishedJUL
ISSN0040-4039
Keywordsbeta-lactam, Enantioselective synthesis, Sphingosine, Wittig reaction
Abstract

Enantiomerically pure (2S,3R,4R)-D-xylo phytosphingosine is synthesized in 36% overall yield in seven steps from known beta-lactam (8) derived from D-mannitol triacetonide. (C) 2009 Elsevier Ltd. All rights reserved.

DOI10.1016/j.tetlet.2009.02.050
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.618
Divison category: 
Organic Chemistry