Enantioselective synthesis of (S)-dapoxetine

TitleEnantioselective synthesis of (S)-dapoxetine
Publication TypeJournal Article
Year of Publication2007
AuthorsSiddiqui, SA, Srinivasan, KV
JournalTetrahedron-Asymmetry
Volume18
Issue17
Pagination2099-2103
Date PublishedSEP
Type of ArticleArticle
ISSN0957-4166
Abstract

An efficient enantioselective synthesis leading directly to (+)-(S)-dapoxetine has been described for the first time using Sharpless asymmetric dihydroxylation, Barton-McCombie deoxygention, and Mitsunobu reaction as the key steps. (C) 2007 Published by Elsevier Ltd.

DOI10.1016/j.tetasy.2007.07.028
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.108
Divison category: 
Organic Chemistry