Enantioselective reduction of ketones and synthesis of 2-methyl-2,3-dihydro-1-benzofuran catalyzed by chiral spiroborate ester
| Title | Enantioselective reduction of ketones and synthesis of 2-methyl-2,3-dihydro-1-benzofuran catalyzed by chiral spiroborate ester |
| Publication Type | Journal Article |
| Year of Publication | 2021 |
| Authors | Patil, HS, Nikalje, MD, Chopade, AU, Chopade, MU |
| Journal | Russian Journal of Organic Chemistry |
| Volume | 57 |
| Issue | 4 |
| Pagination | 611-618 |
| Date Published | APR |
| Type of Article | Article |
| ISSN | 1070-4280 |
| Keywords | 2-methyl-2, 3-dihydro-1-benzofuran, asymmetric reduction, spiroborate ester |
| Abstract | Asymmetric reduction of homobenzylic ketones was achieved through the use of chiral spiroborate ester catalyst. The catalyst is applicable for both analytical and industrial purposes since it is not sensitive to air and moisture. A rapid synthetic route has been developed for the preparation of (S)-2-methyl-2,3-dihydro-1-benzofuran via enantioselective reduction of homobenzylic ketone in the presence of a chiral spiroborate catalyst as the key step. |
| DOI | 10.1134/S1070428021040163 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 0.723 |
Divison category:
Organic Chemistry
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