Enantio- and diastereocontrolled total synthesis of (+)-strictifolione
| Title | Enantio- and diastereocontrolled total synthesis of (+)-strictifolione |
| Publication Type | Journal Article |
| Year of Publication | 2010 |
| Authors | Kumar, P, Pandey, M, Gupta, P, S. Naidu, V, Dhavale, DD |
| Journal | European Journal of Organic Chemistry |
| Issue | 36 |
| Pagination | 6993-7004 |
| Date Published | DEC |
| ISSN | 1434-193X |
| Keywords | Asymmetric synthesis, Hydrolytic kinetic resolution, lactones, Natural products, organocatalysis, Ring-closing metathesis, Total synthesis |
| Abstract | A concise and practical enantioselective synthesis of (+)-strictifolione has been achieved in high diastereomeric excess using Jacobsen's hydrolytic kinetic resolution, proline-catalyzed sequential alpha-aminoxylation and Horner-Wadsworth-Emmons olefination of aldehyde and cross olefin/ring-closing metathesis as the key steps. |
| DOI | 10.1002/ejoc.201001221 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.206 |
Divison category:
Organic Chemistry