Enantio- and diastereocontrolled total synthesis of (+)-boronolide
| Title | Enantio- and diastereocontrolled total synthesis of (+)-boronolide |
| Publication Type | Journal Article |
| Year of Publication | 2006 |
| Authors | Kumar, P, Naidu, SV |
| Journal | Journal of Organic Chemistry |
| Volume | 71 |
| Issue | 10 |
| Pagination | 3935-3941 |
| Date Published | MAY |
| Type of Article | Article |
| ISSN | 0022-3263 |
| Abstract | An efficient stereoselective total synthesis of (+)-boronolide from valeraldehyde is described. The key steps include a Sharpless asymmetric hydroxylation, a chelation-controlled vinyl Grignard reaction followed by a Sharpless asymmetric epoxidation, hydrolytic kinetic resolution, and a ring-closing metathesis. |
| DOI | 10.1021/jo0603781 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 4.785 |
Divison category:
Organic Chemistry