Efficient total synthesis of decarestrictine D

TitleEfficient total synthesis of decarestrictine D
Publication TypeJournal Article
Year of Publication2008
AuthorsGuptali, P, Kumar, P
JournalEuropean Journal of Organic Chemistry
Issue7
Pagination1195-1202
Date PublishedMAR
Type of ArticleArticle
ISSN1434-193X
KeywordsCross metathesis, Hydrolytic kinetic resolution, Macrolides, Ring-closing metathesis, sharpless asymmetric dihydroxylation
Abstract

An efficient total synthesis of decarestrictine D has been achieved using cross-metathesis or ring-closing metathesis and Yamaguchi macrolactonization as key steps. The stereogenic centres were generated by means of hydrolytic kinetic resolution (HKR) and Sharpless asymmetric dihydroxylation (AD).

DOI10.1002/ejoc.200700868
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)3.068
Divison category: 
Organic Chemistry