Efficient synthesis of varenicline

TitleEfficient synthesis of varenicline
Publication TypeJournal Article
Year of Publication2010
AuthorsPasikanti, S, D. Reddy, S, Venkatesham, B, Dubey, PK, Iqbal, J, Das, P
JournalTetrahedron Letters
Volume51
Issue1
Pagination151-152
Date PublishedJAN
AbstractSynthesis of varenicline the antismoking drug has been achieved in six steps with 10% overall yield. A Diels-Alder reaction, oxidative cleavage of an olefin and reductive amination remain as key steps in the synthesis (C) 2009 Elsevier Ltd. All rights reserved.
DOI10.1016/j.tetlet.2009.10.107
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.347
Divison category: 
Organic Chemistry