Efficient synthesis of the opioid analgesic (R)-phenampromide via an aziridinium ion

TitleEfficient synthesis of the opioid analgesic (R)-phenampromide via an aziridinium ion
Publication TypeJournal Article
Year of Publication2017
AuthorsMujahid, M, Mujumdar, P, Sasikumar, M, Deshmukh, SP, Muthukrishnan, M
JournalTetrahedron-Asymmetry
Volume28
Issue7
Pagination983-986
Date PublishedJUL
Type of ArticleArticle
AbstractA simple and efficient synthesis of the opioid analgesic agent (R)-phenampromide with high enantiopurity (> 99% ee) via the formation of an aziridinium ion as a key step using commercially available starting material is described. (C) 2017 Elsevier Ltd. All rights reserved.
DOI10.1016/j.tetasy.2017.06.001
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.108
Divison category: 
Organic Chemistry

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