Efficient synthesis of azetidine-2,3-diones from L-(+)-diethyl tartrate
| Title | Efficient synthesis of azetidine-2,3-diones from L-(+)-diethyl tartrate |
| Publication Type | Journal Article |
| Year of Publication | 2007 |
| Authors | Chincholkar, PM, Puranik, VG, Deshmukh, ARakeeb A |
| Journal | Synlett |
| Issue | 14 |
| Pagination | 2242-2246 |
| Date Published | SEP |
| Type of Article | Article |
| ISSN | 0936-5214 |
| Keywords | Cycloaddition, imines, lactams, spiro compounds, stereoselective synthesis |
| Abstract | A convenient route to enantiopure azetidine-2,3-diones is described. The chiral ketene generated from commercially available L-(+)-diethyl tartrate on Staudinger cycloaddition with different imines gave spiro-beta-lactams in good yields. These spiro-beta-lactams were transformed into azetidine-2,3-diones in excellent yields in a two-step process. |
| DOI | 10.1055/s-2007-985563 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.323 |
Divison category:
Center for Material Characterization (CMC)
Organic Chemistry
Physical and Materials Chemistry