Efficient synthesis of 1,8-dioxo-octahydro-xanthene derivatives promoted by a room temperature ionic liquid at ambient conditions under ultrasound irradiation
Title | Efficient synthesis of 1,8-dioxo-octahydro-xanthene derivatives promoted by a room temperature ionic liquid at ambient conditions under ultrasound irradiation |
Publication Type | Journal Article |
Year of Publication | 2008 |
Authors | Venkatesan, K, Pujari, SS, Lahoti, RJ, Srinivasan, KV |
Journal | Ultrasonics Sonochemistry |
Volume | 15 |
Issue | 4 |
Pagination | 548-553 |
Date Published | APR |
Type of Article | Article |
ISSN | 1350-4177 |
Keywords | aldehydes, ambient conditions, Bronsted acidity, dimedone, Ionic liquid, Ultrasound, Xanthenes |
Abstract | The condensation reaction involving an aldehyde and diketone was efficiently promoted by the Ionic liquid, [Hbim]BF(4) (IL) as a reaction medium with methanol as co-solvent at ambient temperature under ultrasonic irradiation to afford the corresponding 1,8-dioxo-octahydroxantliene (xanthene) derivatives in excellent yields. The advantages of this method include among others the use of a recyclable, non-volatile ionic liquid, which promotes this protocol under ambient temperature without the requirement of ally added catalyst. The reaction times and yields are compared with p-TSA catalyzed synthesis of xanthenes under thermal conditions, which is also reported for the first time under our reaction conditions. (c) 2007 Elsevier B.V. All rights reserved. |
DOI | 10.1016/j.ultsonch.2007.06.001 |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 4.456 |