Efficient synthesis of 1,8-dioxo-octahydro-xanthene derivatives promoted by a room temperature ionic liquid at ambient conditions under ultrasound irradiation

TitleEfficient synthesis of 1,8-dioxo-octahydro-xanthene derivatives promoted by a room temperature ionic liquid at ambient conditions under ultrasound irradiation
Publication TypeJournal Article
Year of Publication2008
AuthorsVenkatesan, K, Pujari, SS, Lahoti, RJ, Srinivasan, KV
JournalUltrasonics Sonochemistry
Volume15
Issue4
Pagination548-553
Date PublishedAPR
Type of ArticleArticle
ISSN1350-4177
Keywordsaldehydes, ambient conditions, Bronsted acidity, dimedone, Ionic liquid, Ultrasound, Xanthenes
Abstract

The condensation reaction involving an aldehyde and diketone was efficiently promoted by the Ionic liquid, [Hbim]BF(4) (IL) as a reaction medium with methanol as co-solvent at ambient temperature under ultrasonic irradiation to afford the corresponding 1,8-dioxo-octahydroxantliene (xanthene) derivatives in excellent yields. The advantages of this method include among others the use of a recyclable, non-volatile ionic liquid, which promotes this protocol under ambient temperature without the requirement of ally added catalyst. The reaction times and yields are compared with p-TSA catalyzed synthesis of xanthenes under thermal conditions, which is also reported for the first time under our reaction conditions. (c) 2007 Elsevier B.V. All rights reserved.

DOI10.1016/j.ultsonch.2007.06.001
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)4.456
Divison category: 
Biochemical Sciences