Efficient, rapid, and regioselective bromination of anilines and phenols with 1-butyl-3-methylpyridinium tribromide as a new reagent/solvent under mild conditions
| Title | Efficient, rapid, and regioselective bromination of anilines and phenols with 1-butyl-3-methylpyridinium tribromide as a new reagent/solvent under mild conditions |
| Publication Type | Journal Article |
| Year of Publication | 2009 |
| Authors | Borikar, SP, Daniel, T, Paul, V |
| Journal | Tetrahedron Letters |
| Volume | 50 |
| Issue | 9 |
| Pagination | 1007-1009 |
| Date Published | MAR |
| ISSN | 0040-4039 |
| Keywords | Bromination, Ionic liquid, Regioselective, [BMPy]Br(3) |
| Abstract | 1-Butyl-3-methylpyridinium tribromide, [BMPy]Br(3) proves to be a highly efficient, regioselective reagent/solvent for nuclear bromination of various anilines and phenols. The synthesis and characterization of the room temperature ionic liquid [BMPy]Br(3) (2) is described. The bromination was carried out in the absence of organic solvents and in most cases the only extraction solvent needed was water. The spent 1-butyl-3-methylpyridinium bromide (1) was easily recycled. (C) 2008 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetlet.2008.12.053 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.618 |
Divison category:
Organic Chemistry