Efficient and improved method for the Biginelli reaction using solid superacid (sulphated SnO2)

TitleEfficient and improved method for the Biginelli reaction using solid superacid (sulphated SnO2)
Publication TypeJournal Article
Year of Publication2005
AuthorsBhosale, RS, Hashmi, AM, Zubaidha, PK, Dongare, MK
JournalHeterocyclic Communications
Volume11
Issue5
Pagination399-402
Date PublishedOCT
Type of ArticleArticle
ISSN0793-0283
KeywordsBiginelli, DHPM, sulphated SnO2
Abstract

One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-one (DHPM) has been effected efficiently by coupling of the three components, aldehyde, ethyl acetoacetate and urea/thiourea in the presence of solid Superacid (sulphated SnO2). The method presented herein is attractive with respect to yield, reaction time, workup procedure and reusable catalyst.

Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)0.828
Divison category: 
Catalysis and Inorganic Chemistry