Efficient and cost effective synthesis of acetamides catalyzed by calcium chloride

TitleEfficient and cost effective synthesis of acetamides catalyzed by calcium chloride
Publication TypeJournal Article
Year of Publication2019
AuthorsSangole, MT, Thorat, SM, Shirsath, S, Deshmukh, SP, Muthukrishnan, M, Mujahid, M
JournalIndian Journal of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry
Volume58
Issue10
Pagination1125-1130
Date PublishedOCT
Type of ArticleArticle
ISSN0376-4699
KeywordsAcetamide, acetylation, Acylation, Amine, CaCl2
AbstractCaCl2 has been found to be an efficient and cost effective catalyst for the rapid synthesis of acetamides in high yields. The use of stoichiometric quantities of acetic anhydride under solvent free conditions without any additional chromatographic purifications makes this protocol a safe alternative to the existing methods.
Type of Journal (Indian or Foreign)Indian
Impact Factor (IF)0.388
Divison category: 
Organic Chemistry

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