Easy and practical approach to access multifunctional cylcopentadiene- and cyclopentene-spirooxindoles via [3+2] annulation
| Title | Easy and practical approach to access multifunctional cylcopentadiene- and cyclopentene-spirooxindoles via [3+2] annulation |
| Publication Type | Journal Article |
| Year of Publication | 2021 |
| Authors | Warghude, PK, Sabale, AS, Dixit, R, Vanka, K, Bhat, RG |
| Journal | Organic & Biomolecular Chemistry |
| Volume | 19 |
| Issue | 19 |
| Pagination | 4338-4345 |
| Date Published | MAY |
| Type of Article | Article |
| ISSN | 1477-0520 |
| Abstract | A highly regioselective [3 + 2] annulation of Morita-Baylis-Hillman (MBH) carbonates of isatin with aurone/thioaurone is developed. Spiroheterocycles such as spirooxindole cyclopentadiene and spirooxindole fused hydroxy cyclopentene derivatives are constructed in one pot by exploring the reactivity of Lewis bases. Combined experimental and density functional theory (DFT) calculations offered an insight into the reaction mechanism. |
| DOI | 10.1039/d1ob00514f, Early Access Date = APR 2021 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.876 |
Divison category:
Physical and Materials Chemistry
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