Easy access to alpha-aryl substituted gamma-ketophosphonates: lewis acid mediated reactions of 1,3-diketones with alpha-hydroxyphosphonates and tandem regioselective C-C bond cleavage
| Title | Easy access to alpha-aryl substituted gamma-ketophosphonates: lewis acid mediated reactions of 1,3-diketones with alpha-hydroxyphosphonates and tandem regioselective C-C bond cleavage |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Pallikonda, G, Chakravarty, M, Sahoo, MKumar |
| Journal | Organic & Biomolecular Chemistry |
| Volume | 12 |
| Issue | 36 |
| Pagination | 7140-7149 |
| Date Published | JUL |
| Type of Article | Article |
| ISSN | 1477-0520 |
| Abstract | A range of alpha-aryl substituted gamma-ketophosphonates is synthesised by Lewis acid mediated reactions of 1,3-diketones and easily accessible, inexpensive benzylic alpha-hydroxyphosphonates in an operationally simple method under solvent-free conditions without exclusion of air/moisture. A regioselective C-C bond cleavage for 1,3-diketones in a tandem fashion has also been demonstrated. Synthesis of a gamma-ketophosphonate with phenol functionality at the a-position (structural analogue of raspberry ketone, a natural product) has also been presented. |
| DOI | 10.1039/c4ob01091d |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.559 |
Divison category:
Catalysis and Inorganic Chemistry