Double intramolecular oxymercuration: stereoselective synthesis of highly substituted bis-tetrahydrofuran
| Title | Double intramolecular oxymercuration: stereoselective synthesis of highly substituted bis-tetrahydrofuran |
| Publication Type | Journal Article |
| Year of Publication | 2006 |
| Authors | Mohapatra, DK, Mohapatra, S, Gurjar, MK |
| Journal | Tetrahedron Letters |
| Volume | 47 |
| Issue | 33 |
| Pagination | 5943-5947 |
| Date Published | AUG |
| Type of Article | Article |
| ISSN | 0040-4039 |
| Keywords | acetogenins, Barton-McCombie deoxygenation, demercuration, intramolecular oxymercuration, unsymmetrical bis-tetrabydrofuran, Wittig reaction |
| Abstract | Stereoselective intramolecular oxymercuration has been demonstrated as the key reaction for the efficient preparation of mono- and dihydroxylated unsymmetrical bis-tetrahydrofuran skeletons present in naturally occurring biologically active acetogenins using carbohydrates. These trans- and syn-selective intramolecular oxymercurations were explored in an enantio selective synthesis of the bis-tetrahydrofuran skeleton of mucoxin. (c) 2006 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetlet.2006.06.049 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.347 |
Divison category:
Organic Chemistry