DNA and PNA as templates for building nanoassemblies via electrostatic complexation with gold nanoparticles

TitleDNA and PNA as templates for building nanoassemblies via electrostatic complexation with gold nanoparticles
Publication TypeJournal Article
Year of Publication2005
AuthorsGourishankar, A, Shukla, S, Pasricha, R, Sastry, M, Ganesh, KN
JournalCurrent Applied Physics
Volume5
Issue2
Pagination102-107
Date PublishedFEB
ISSN1567-1739
KeywordsDNA, DNA-gold nanoparticle interactions, nanoassemblies, PNA
Abstract

Organisation of nanoparticles on structurally well-defined templates is a first step towards creating nanomachines. In this respect, nucleic acids are ideal structural templates and a variety of secondary structures realizable from DNA/RNA - e.g., duplexes, hairpins, triplexes, cruciforms, tetraplexes can be exploited to engineer nanoparticle organization at will. We have used oligonucleotides and their analogues such as phosphorothioates and peptide nucleic acids to electrostatically encapsulate cationic-capped gold nanoparticles. This article describes synthesis and characterization of DNA/PNA-gold nanoparticle composites using TEM and UV-T-m techniques. These types of assemblies may have potential for creating nanowires and lithographic circuits. (C) 2004 Elsevier B.V. All rights reserved.

DOI10.1016/j.cap.2004.06.020
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)2.144
Divison category: 
Organic Chemistry