DNA and PNA as templates for building nanoassemblies via electrostatic complexation with gold nanoparticles
Title | DNA and PNA as templates for building nanoassemblies via electrostatic complexation with gold nanoparticles |
Publication Type | Journal Article |
Year of Publication | 2005 |
Authors | Gourishankar, A, Shukla, S, Pasricha, R, Sastry, M, Ganesh, KN |
Journal | Current Applied Physics |
Volume | 5 |
Issue | 2 |
Pagination | 102-107 |
Date Published | FEB |
ISSN | 1567-1739 |
Keywords | DNA, DNA-gold nanoparticle interactions, nanoassemblies, PNA |
Abstract | Organisation of nanoparticles on structurally well-defined templates is a first step towards creating nanomachines. In this respect, nucleic acids are ideal structural templates and a variety of secondary structures realizable from DNA/RNA - e.g., duplexes, hairpins, triplexes, cruciforms, tetraplexes can be exploited to engineer nanoparticle organization at will. We have used oligonucleotides and their analogues such as phosphorothioates and peptide nucleic acids to electrostatically encapsulate cationic-capped gold nanoparticles. This article describes synthesis and characterization of DNA/PNA-gold nanoparticle composites using TEM and UV-T-m techniques. These types of assemblies may have potential for creating nanowires and lithographic circuits. (C) 2004 Elsevier B.V. All rights reserved. |
DOI | 10.1016/j.cap.2004.06.020 |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 2.144 |