Design, synthesis and DNA/RNA binding studies of nucleic acids comprising stereoregular and acyclic polycarbamate backbone: polycarbamate nucleic acids (PCNA)

TitleDesign, synthesis and DNA/RNA binding studies of nucleic acids comprising stereoregular and acyclic polycarbamate backbone: polycarbamate nucleic acids (PCNA)
Publication TypeJournal Article
Year of Publication2010
AuthorsMadhuri, V, Kumar, VA
JournalOrganic & Biomolecular Chemistry
Volume8
Issue16
Pagination3734-3741
Date PublishedJun
ISSN1477-0520
Abstract

The designed, chiral, acyclic polycarbamate nucleic acids (PCNA) exhibited sequence and orientation specific binding to nucleic acids. Complexes of PCNA with DNA were as stable as PNA:DNA complexes and those with RNA were as stable as natural DNA:RNA complexes.

DOI10.1039/c003405n
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)3.451
Divison category: 
Organic Chemistry