Design, synthesis and DNA/RNA binding studies of nucleic acids comprising stereoregular and acyclic polycarbamate backbone: polycarbamate nucleic acids (PCNA)
Title | Design, synthesis and DNA/RNA binding studies of nucleic acids comprising stereoregular and acyclic polycarbamate backbone: polycarbamate nucleic acids (PCNA) |
Publication Type | Journal Article |
Year of Publication | 2010 |
Authors | Madhuri, V, Kumar, VA |
Journal | Organic & Biomolecular Chemistry |
Volume | 8 |
Issue | 16 |
Pagination | 3734-3741 |
Date Published | Jun |
ISSN | 1477-0520 |
Abstract | The designed, chiral, acyclic polycarbamate nucleic acids (PCNA) exhibited sequence and orientation specific binding to nucleic acids. Complexes of PCNA with DNA were as stable as PNA:DNA complexes and those with RNA were as stable as natural DNA:RNA complexes. |
DOI | 10.1039/c003405n |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 3.451 |
Divison category:
Organic Chemistry