Design and synthesis of dephosphono dna analogues containing 1,2,3-triazole linker and their UV-melting studies with DNA/RNA
| Title | Design and synthesis of dephosphono dna analogues containing 1,2,3-triazole linker and their UV-melting studies with DNA/RNA |
| Publication Type | Journal Article |
| Year of Publication | 2012 |
| Authors | Madhuri, V, Kumar, VA |
| Journal | Nucleosides Nucleotides & Nucleic Acids |
| Volume | 31 |
| Issue | 1-3 |
| Pagination | 97-111 |
| Date Published | JAN |
| ISSN | 1525-7770 |
| Keywords | isostere, Oligonucleotide analogues, Triazole, UV melting |
| Abstract | This article describes the synthesis of 3'/5' linked 1,2,3-triazolyl dithymidine derivatives, their incorporation into oligonucleotides, and evaluation of their thermal stabilities toward complementary DNA/RNA. |
| DOI | 10.1080/15257770.2011.644100 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 0.713 |
Divison category:
Organic Chemistry