Dendrimeric amide- and carbamate-linked lysine-based efficient molecular transporters

TitleDendrimeric amide- and carbamate-linked lysine-based efficient molecular transporters
Publication TypeJournal Article
Year of Publication2017
AuthorsYadav, AKumar, Dey, N, Chattopadhyay, S, Ganguli, M, Fernandes, M
JournalOrganic & Biomolecular Chemistry
Volume15
Issue45
Pagination9579-9584
Date PublishedDEC
Type of ArticleArticle
Abstract

Amide- and carbamate-linked dendrimeric oligomers are reported as molecular transporters. They effectively complex with pDNA and transport it into cells at an efficiency superior to Lipofectamine, when complexation is carried out by incubation overnight. The carbamate-linked K2C is superior to amide-linked K2A; their pDNA complexes have very low associated cytotoxicity.

DOI10.1039/c7ob02552a
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)3.559
Divison category: 
Organic Chemistry

Add new comment