Cu(OTf)(2) catalyzed high yield synthesis of hantzsch 1,4-dihydropyridines

TitleCu(OTf)(2) catalyzed high yield synthesis of hantzsch 1,4-dihydropyridines
Publication TypeJournal Article
Year of Publication2007
AuthorsParaskar, AS, Sudalai, A
JournalIndian Journal of Chemistry Section B-Organic Chemistry including Medicinal Chemistry
Volume46
Issue2
Pagination331-335
Date PublishedFEB
Type of ArticleArticle
ISSN0376-4699
Keywords4-dihydropyridines, anti-hypertensive drug, calcium channel blockers, cardiovascular diseases, Hantzsch 1, three-component condensation
Abstract

Copper(II) triflate catalyzes efficiently the three-component condensation of aldehydes, beta-ketoesters and ammonium acetate in acetonitrile at 25 degrees C to afford the corresponding Hantzsch 1,4-dihydropyridines in high yields.

Type of Journal (Indian or Foreign)

Indian

Impact Factor (IF)

0.471

Divison category: 
Chemical Engineering & Process Development