Cu(OTf)(2)-catalyzed alpha-halogenation of ketones with 1,3-dichloro-5,5 `-dimethylhydantoin and N-bromosuccinimide

TitleCu(OTf)(2)-catalyzed alpha-halogenation of ketones with 1,3-dichloro-5,5 `-dimethylhydantoin and N-bromosuccinimide
Publication TypeJournal Article
Year of Publication2009
AuthorsJagdale, AR, Chouthaiwale, PV, Sudalai, A
JournalIndian Journal of Chemistry Section B-Organic Chemistry including Medicinal Chemistry
Volume48
Issue10
Pagination1424-1430
Date PublishedOCT
ISSN0376-4699
KeywordsBromination, Catalyst, chlorination, copper (II), Ketone, Lewis acid
Abstract

Copper(II) triflate catalyses efficiently the alpha-halogentation of aryl or alkyl ketones with 1,3-dichloro-5,5'-dimethyl-hydantoin and N-bromosaccinimde to give the corresponding alpha,alpha-dichloroketones and alpha-bromoketones in high yield with excellent product selectivity.

Type of Journal (Indian or Foreign)

Indian

Impact Factor (IF)

0.562

Divison category: 
Chemical Engineering & Process Development