Copper(I) bromide-catalyzed carbonylative coupling of aryl halides with phenols, alcohols and amines using sodium cyanide as C-1 source: a synthesis of carboxylic acid derivatives

TitleCopper(I) bromide-catalyzed carbonylative coupling of aryl halides with phenols, alcohols and amines using sodium cyanide as C-1 source: a synthesis of carboxylic acid derivatives
Publication TypeJournal Article
Year of Publication2014
AuthorsPrasad, PK, Sudalai, A
JournalAdvanced Synthesis & Catalysis
Volume356
Issue10
Pagination2231-2238
Date PublishedJUL
ISSN1615-4150
Keywordsanhydrides, C-1 building blocks, isochroman-1-ones, lactams, lactones
Abstract

A new ``carbon monoxide-free'' synthesis of carboxylate derivatives via carbonylative coupling of aryl bromides with phenols, alcohols, amines and acids in the presence of copper(I) bromide as catalyst and sodium cyanide in a stoichiometric amount has been developed. Its intramolecular version provides for the preparation of lactones (e.g., isochroman-1-ones and isobenzfuranones), imides, anhydrides and lactams in excellent yields (73-96%).

DOI10.1002/adsc.201301155
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

6.453

Divison category: 
Chemical Engineering & Process Development